The SLC13 gene family of sodium sulphate/carboxylate cotransporters
نویسندگان
چکیده
منابع مشابه
Dynamic imaging of the sodium phosphate cotransporters.
Although in vivo and cell culture studies have provided useful information about the regulation of the sodium phosphate (NaPi) cotransporters, such studies are unable to provide information at the molecular level about interactions between proteins. The NaPi proteins are found within both intestinal and renal brush border microvilli, and previous work has shown that these microvilli contain sca...
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Several apical iodide translocation pathways have been proposed for iodide efflux out of thyroid follicular cells, including a pathway mediated by the sodium-coupled monocarboxylate transporter 1 (SMCT1), which remains controversial. Herein, we evaluate structural and functional similarities between SMCT1 and the well-studied sodium-iodide symporter (NIS) that mediates the first step of iodide ...
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Although water permeation across cell membranes occurs through several types of membrane proteins, the only permeation mechanism resolved at atomic scale is that through aquaporins. Crystallization of the Vibrio parahaemolyticus sodium-galactose transporter (vSGLT) allows investigation of putative water permeation pathways through both vSGLT and the homologous human Na-glucose cotransporter (hS...
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The physiological regulation of renal Pi reabsorption is mediated by renal type II Na/Pi cotransporters (type IIa and type IIc). The type IIa transporter is regulated, among other factors, by dietary Pi intake and parathyroid hormone (PTH). The PTH-induced inhibition of Pi reabsorption is mediated by endocytosis of the type IIa transporter from the brush-border membrane and subsequent lysosomal...
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The Na+-dependent glucose cotransporters (SGLT) are a family of glucose transporters that mediate an active, sodium-linked transport process against an electrochemical gradient. The SGLT are known to play important roles in absorption of dietary D-glucose and D-galactose from the intestinal lumen and in the reabsorption of D-glucose from the glomerular filtrate in kidney. To study the role and ...
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ژورنال
عنوان ژورنال: Pfl�gers Archiv European Journal of Physiology
سال: 2004
ISSN: 0031-6768,1432-2013
DOI: 10.1007/s00424-003-1207-8